Copaiba oleoresin attenuates weight gain without alter inflammatory and redox system markers in adipose tissue of healthy animals
DOI:
https://doi.org/10.36560/16420231694Keywords:
copaiba, adipose tissue, inflammation, redox systemAbstract
Adipose tissue produces and releases a variety of adipokines, which participate in regulating physiologic and pathologic processes. Active compounds have been described in copaiba oleoresin, demonstrating therapeutics effects. However, there is no data the effects of copaiba oleoresin on adipose tissue. Thus, the action of copaiba oleoresin on inflammatory and redox system markers was evaluated. Male Wistar rats were randomly assigned to receiving commercial chow (C, n=7) or commercial chow + copaiba oleoresin (CO, n=7), for eight weeks. Copaiba oleoresin was given by gavage at a dose of 200 mg/kg/dia. C animals received vehicle, at equivalent volume, by gavage. Data show copaiba oleoresin supplementation reduces weight gain and adiposity without alter metabolic parameters and inflammatory and redox system markers in adipose tissue. These results indicate that copaiba oleoresin was effective to attenuate weight gain and present no undesired outcomes to adipose tissue of healthy animals.
Keywords: copaiba, adipose tissue, inflammation, redox system
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