Bioactive Compounds and antioxidant potential of Rhamnidium elaeocarpum (Rhamnaceae)
DOI:
https://doi.org/10.36560/18320252060Palavras-chave:
Rhamnidium elaeocarpum, antioxidant activity, flavonoids, sterols, DPPH, ABTS, lipid peroxidationResumo
This study investigates the antioxidant potential and chemical composition of Rhamnidium elaeocarpum extracts. The purpose was to evaluate the bioactive properties of the plant’s ethanolic extract and identify the key compounds responsible for its effects. The methods involved the preparation of ethanolic extracts followed by assays to measure antioxidant activity, including DPPH radical scavenging, ABTS assay, and lipid peroxidation inhibition. The extract was also analyzed for its phytochemical composition through chromatography techniques. The results showed that the ethanolic extract exhibited significant antioxidant activity, with high radical scavenging capacity and strong inhibition of lipid peroxidation. Major bioactive compounds, including flavonoids and sterols, were identified, which are likely responsible for the observed effects.
Referências
Richardson, J.E.; Chatrou, L.W.; Mols, J.B.; Erkens, R.H.; Pirie, M.D. Historical biogeography of two cosmopolitan families of flowering plants: Annonaceae and Rhamnaceae. Philos. Trans. R. Soc. Lond. B Biol. Sci., v. 359, p. 1495-1508, 2004.
Alarcón, J.; Cespedes, C.L. Chemical constituents and biological activities of South American Rhamnaceae. Phytochem. Rev., v. 14, p. 389-401, 2015.
Lima, R.B.; Giulietti, A.M. Synonymies and typification of the Rhamnaceae of Brazil. Acta Bot. Bras., v. 28, p. 376-381, 2014.
Pott, P.; Pott, J.V. Plantas do Pantanal. Corumbá: Embrapa, 1994. p. 244-245.
Lorenzi, H. Árvores brasileiras: manual de identificação e cultivo de plantas arbóreas do Brasil. Nova Odessa: Instituto Plantarum, 1998. p. 89-91.
Oliveira, T.B.; Soares, R.L.; Tresvesol, L.M.F.; Branquinho, D.S.P.; Bara, M.T.F.; Fiuza, T.S.; Rezende, M.H.; Paula, J.R. Caracterização das folhas e cascas de Rhamnidium elaeocarpum Reissek. Latin Am. J. Pharm., v. 29, p. 534-541, 2010.
Kauffmann, A.C.; Oliveira, R.G.S.P.; Dourado, T.A.; Soares, I.N.; Sousa, P.T.; Ribeiro, T.A.N.; Jacinto, M.J.; Souza, G.L.; Judice, W.A.S.; Emiliano, M.F.C.; Vianna, L.S.; Carvalho, M.G.; Silva, V.C.P. Eleocarpanthraquinone, a novel anthraquinone from Rhamnidium elaeocarpum (Rhamnaceae). Tetrahedron Lett., v. 61, p. 152489, 2020.
Ohkawa, H.; Ohishi, N.; Yagi, K. Assay of lipid peroxidation in animals and tissues by thiobarbituric acid reaction. Anal. Biochem., v. 95, p. 351-358, 1979.
Parthasarathy, S.; Azizi, J.B.; Ramanathan, S.; Ismail, S.; Sasidharan, S.; Said, M.I.M.; Mansor, S.M. Evaluation of antioxidant and antibacterial activities of aqueous, methanolic and alkaloid extracts from Mitragyna speciosa (Rubiaceae family) leaves. Molecules, v. 14, p. 3964-3974, 2009.
Aderogba, M.A.; Kgatle, D.T.; Macgaw, L.J.; Eloff, J.N. Antifungal and antibacterial activities of plant extracts. S. Afr. J. Bot., v. 79, p. 125-131, 2012.
Kojima, H.; Sato, N.; Hatano, A.; Ogura, H. Flavonoid glycosides from the leaves of Zelkova serrata. Phytochem., v. 29, p. 2351-2355, 1990.
Silva, J.P.R.; Policarpo, I.S.; Chaves, T.P.; Coutinho, H.D.M.; Alves, H.S. A glycosylated β-sitosterol, isolated from Tacinga inamoena (Cactaceae), enhances the antibacterial activity of conventional antibiotics. S. Afr. J. Bot., v. 133, p. 193-200, 2020.
Sharma, O.P.; Bhat, T.K. DPPH antioxidant assay: A review. Food Chem., v. 133, p. 1202-1205, 2009.
Silva, J.R.; Souza, A.O.; Anjos, I.C.; Pádua, G.M.S.; Vieira, L.C.C.; Gai, B.M. Evaluation of chalcones derivatives in lipid peroxidation reduction induced by Fe²⁺/EDTA in vitro. Res. Soc. Dev., v. 12, p. e16012139541, 2023.
Huang, D.; Ou, B.; Prior, R.L. The chemistry behind antioxidant capacity assays. J. Agric. Food Chem., v. 53, p. 1841-1856, 2005.
Downloads
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2025 Scientific Electronic Archives
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
A revista se reserva o direito de fazer alterações nas regras originais, na ortografia e na ordem gramatical, a fim de manter o idioma de culto padrão, respeitando, no entanto, o estilo dos autores. Os artigos publicados são de propriedade da revista Scientific Electronic Archives, tornando-se sua reimpressão total ou parcial, sujeitos à autorização expressa da direção da revista. A fonte original da publicação deve ser mantida. Os originais não serão devolvidos aos autores. As opiniões expressas pelos autores dos artigos são de sua exclusiva responsabilidade.
The journal reserves the right to make changes to the original rules, spelling and grammatical order, in order to keep the language of worship default, respecting, however, the style of the authors. Articles published are the property of Scientific Electronic Archives magazine, becoming its total or partial reprint, subject to the express authorization of the direction of the journal. The original source of publication should be retained. The originals will not be returned to the authors. Opinions expressed by authors of articles are solely your responsibility.
This journal uses the License Creative Commons Atribuição 4.0 Internacional.
1.png)
