The floral extract of Jacaranda ulei Bureau & K. Schum. inhibited Candida?
DOI:
https://doi.org/10.36560/14820211314Keywords:
Bignoniaceae, Jacaranda Genus, Candida albicans, Candida tropicalis, Candida kruseiAbstract
The objective of the work was to verify the antifungal activity on Candida from the hydroethanolic floral extract of Jacaranda ulei. Flowers of J. ulei were collected in december 2020 in Cerrado in a restricted sense. The extract was produced by maceration in a 70% hydroethanolic solution. The antifungal assay was performed using the disc diffusion method in different concentrations 500-15.62 mg mL-1 on Candida albicans, C. tropicalis, C. guilliermondii and C. krusei. The floral extract showed high potential as an antifungal agent on Candida tropicalis between 25.6-11.1 mm, C. guilliermondii between 32.6-10.7 mm and C. krusei between 31.3-14.3 mm. Candida albicans has been shown to be resistant at concentrations below 500 mg mL-1 with an antibiosis halo of 10.4 mm. Further studies should be carried out verifying the synergism of the Jacaranda ulei floral extract with the reference antifungal and the analysis of the chemical profile of the extract.
References
ALMEIDA, K.L., SILVA, L.P.,SILVA, G.A., NETO, C.M.S., PRADO, R.S. Atividade inibitória de Handroanthus serratifolius (Bignoniaceae) sobre Candida albicans. REFACER Rev El da Faculdade de Ceres, v. 4, n.2, p. 1-16, 2015. http://periodicos.unievangelica.edu.br/index.php/refacer/article/view/3350
ARENDRUP, M.C., PATTERSON, T.F. Multidrug-resistant Candida: epidemiology, molecular mechanisms, and treatment. J Infec Dis. vol. 216, n. 3, p. S445-S451, 2017. https://doi.org/10.1093/infdis/jix131
ASSIS, P.A. Atividade antifúngica de extratos depositados no banco de extratos de plantas do bioma Cerrado e de substâncias isoladas de Matayba guianensis. 168 f. 2013. Dissertação. (Mestrado em Ciências da Saúde). Universidade de Brasília, DF, Brasil. 2013.
AZIE, N., NEOFYTOS, D., PFALLER, M., MEIER-KRIESCHE, H-U., QUAN, S-P., HORN, D. The PATH (prospective antifungal therapy) Alliance® registry and invasive fungal infections: update 2012. Diagn Microbiol Infect Dis. vol. 73, n. 4, p. 293-300, 2012. https://doi.org/10.1016/j.diagmicrobio.2012.06.012
BARBOSA FILHO, T.P., NETO, H.D. Preparação de derivados do lapachol em meio ácido e em meio básico: uma proposta de experimentos para a disciplina de química orgânica experimental. Rev Quím Nova, vol. 36, n. 2, p. 331-334, 2013.
DIAGNANI, M.C., SOLOMKIN, J.S., ANAISSIE, E.J. Candida. In: ANAISSIE, E.J., MCGINNIS, M.R., PFALLER, M.A. Clinical Mycology, 2nd, Ed., Amsterdan: Elsevier, 2009.
DREBES, T., ETHUR, E.M., AVANCINI, C.A.M. Triagem fitoquímica e atividade antibacteriana dos extratos aquoso e hidroetanólico brutos de Jacaranda micrantha Cham. (“caroba”) sobre cepas de Staphylococcus coagulase positiva e Salmonella spp. padrões e isoladas em produtos de origem animal. Archives of Veterinary Science, vol. 23, n. 2, p. 27-39, 2018. http://dx.doi.org/10.5380/avs.v23i2.51197
EDMOND, M.B., WALLACE, S.E., McCLISH, D.K., PFALLER, M.A., JONES, R.N., WENZEL, R.P. Nosocomial bloodstram infections in United States hospitals: a three-years analysis. Clin Infect Dis, vol. 29, n. 2, p. 239-244, 1999. https://doi.org/10.1086/520192
FARIAS, K.S., SANTOS, T.S.N., PAIVA, M.R.A.B., ALMEIDA, S.M.L., GUEDES, P.T., VIANNA, A.C.A. FAVARO, S.P., BUENO, N.R., CASTILHO, R.O. Antioxidant properties of species from the Brazilian cerrado by different assays. Rev Bas Pl Med, vol. 15, p. 520-528, 2013. https://doi.org/10.1590/S1516-05722013000400008
FUKUDA, W.S. Propagação in vitro de Jacaranda ulei Bureau & K. Schum. (Bignoniaceae). f. 111. 2011. Dissertação (Botânica). Universidade de Brasília. 2011.
JÚNIOR, G.A.V., GUIMARÃES, M.S.A., BAPTISTA, A.M.G., BAPTISTA, A.B. Plantas medicinais e leishimaniose cutânea: uma revisão. Rev Cereus. vol. 11, n. 4, p. 84-98, 2019. http://www.ojs.unirg.edu.br/index.php/1/article/view/2758
LOHMANN, L.G., TAYLOR, C.M. A new generic classification of tribe Bignonieae (Bignoniaceae). Ann Missouri Bot Gard. Vol. 99, p. 348-489, 2014. https://doi.org/10.3417/2003187
LOHMANN, L.G., FIRETTI, F., GOMES, B.M. Flora das cangas da Serra dos Carajás, Pará, Brasil: Bignoniaceae. Rodriguésia, vol. 69, n. 3, p. 1063-1079, 2018. http://dx.doi.org/10.1590/2175-7860201869313
LOHMANN, L.G. Bignoniaceae. In: FORZZA, R.C. Editor. Flora do Brasil 2020 em construção. Jardim Botânico do Rio de Janeiro. Disponível em: http://reflora.jbrj.gov.br/reflora/floradobrasil/FB119 acesso em: 22 dez 2020.
MARCONDES, A.F., OLIVEIRA, M.A. Cerrado and ethnoveterinary: o que se sabe em Jataí – GO? Braz J Agroecol. vol. 6, n. 3, p. 49-61, 2011.
MENEZES, T.O.A., ALVES, A.C.B.A., VIEIRA, J.M.S., MENEZES, S.A.F., ALVES, B.P., MENDONÇA, L.C.V. Avaliação in vitro da atividade antifúngica de óleos e extratos de plantas da região amazônica sobre cepa de Candida albicans. Rev. Odont. vol. 38, n. 3, p. 184-191, 2009. http://host-article-assets.s3.amazonaws.com/rou/588018907f8c9d0a098b4ce2/fulltext.pdf
MIRANDA, T.D., PALHARES, D., CURY, N.F., PEREIRA, L.A.R., SILVEIRA, C.E.S. Comparative wood and bark anatomy of stem, root and xylopodium of Jacaranda ulei (Bignoniaceae). Balduina, n. 64, p. 01-18, 2018. https://doi.org/10.5902/2358198032114
MOSTAFA, N., ELDASHAN, O., SINGGAB, A. The genus Jacaranda (Bignoniaceae): an updated review. Pharmacog Communications. vol. 4, n. 3, p. 31-39, 2014. http://phcogfirst.com/article/759
NUNES, G.P., SILVA, M.F., RESENDE, U.M. SIQUEIRA, J.M. Medicinal plants from herb sellers operating in downtown Campo Grande, Mato Grosso do Sul, Brazil. Braz J Pharmacog. vol. 13, n. 2, p. 83-95, 2003. https://doi.org/10.1590/S0102-695X2003000200004
NUNES, P.H., FERREIRA, H.D., BORGES, L.L., SÁ, S., CUNHA, L.C., NETO, J.R.O., PAULA, J.R., FIUZA, T.S. Morphoanatomic study of Jacaranda ulei and variability of its volatile oils. Rev Bras Farmacog. vol. 30, p. 718-722, 2020. https://doi.org/10.1007/s43450-020-00099-1
PAIS, P., GALOCHA, M., VIANA, R., CAVALHEIRO, M., PEREIRA, D., TEIXEIRA, M.C. Microevolution of the pathogenic yeasts Candida albicans and Candida glabrata during antifungal therapy and host infection. Microb Cell. vol. 6, n. 3, p. 142-149, 2019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402363/
PEREIRA, E.M., MACHADO, T.B., LEAL, I.C.R. JESUS, D.M., DAMASO, C.R.A., PINTO, A.V. Tabebuia avellanedae naphthoquinones: activity against methicillin-resistant staphylococcal strains, cytotoxic activity and in vivo dermal irritability analysis. Ann Clin Microbiol Antimicrob. vol. 5, n. 1, p. 5, 2006. https://doi.org/10.1186/1476-0711-5-5
PFALLER, M.A., DIEKEMA, D.J. Epidemiology of invasive mycoses in North America. Crit Rev Microbiol. vol. 36, n. 1, p. 1-53, 2010. https://doi.org/10.3109/10408410903241444
RAMOS, R.S., SARMENTO, P.A., LINS, T.H., LÚCIO, I.M.L., CONSERVA, L.M., BASTOS, M.L.A. Atividade antimicrobiana in vitro dos extratos hexânico e etanólico das folhas de Zeyheria tuberculosa. Revista da Rede de Enfermagem do Nordeste, vol. 13, n. 5, p. 1015-1024, 2012. https://www.redalyc.org/pdf/3240/324027984006.pdf
RIBEIRO, T.G., CHÁVEZ-FUMAGALLI, M.A., VALADARES, D.G. et al. Antileishmanial activity and citotoxity of Brazilian plants. Exp Parasitol. vol. 143, p. 60-68, 2014. https://doi.org/10.1016/j.exppara.2014.05.004
SILVA, P.R.D., STEFENON, V.M. Histological features, starch accumulation and sprouting in the early root development of Jacaranda ulei (Bignoniaceae). An Acad Bras Cienc. vol. 86, n. 1, p. 271-276, 2014. http://dx.doi.org/10.1590/0001-37652013109212
SILVEIRA, C.E.S., FUKUDA, W.S., MIRANDA, T.D., PALHARES, D., PEREIRA, L.A.R. Jacaranda ulei Bureau and K. Schum. (Bignoniaceae): in vitro seedling developmental study as contribution towards the domestication of this medicinal Brazilian savannah species. J Pharmacog Phytochem. vol. 2, n. 4, p. 85-89, 2013. https://www.phytojournal.com/archives/2013/vol2issue4/PartB/19.1.pdf
SOUZA, C.N., REZENDE, A.A., GASPARINO, E.C. Pollen morphology of Bignoniaceae from Brazilian forest fragments and its systematic significance. Palynology. vol. 43, n. 2, p. 333-347, 2019. https://doi.org/10.1080/01916122.2018.1476924
UDULUTSCH, R.G., ASSIS, M.A., DIAS, P. Adenocalymma calcareum sp. nov. (Bignoniaceae) from Brazilian Amazonia and a key to the Amazonian species of the genus. Nordic J Bot. vol. 27, p. 449-453, 2009. https://doi.org/10.1111/j.1756-1051.2009.00490.x
VIEIRA, A.J.H., SANTOS, J.I. Mecanismos de resistência de Candida albicans aos antifúngicos anfotericina B, fluconazol e caspofungina. RBAC. vol. 49, n. 3, p. 235-239, 2017.
VIU, A.F.M., VIU, M.A.O. Cerrado e etnoveterinária: o que se sabe em Jataí – GO? Rev Bras Agroecol. vol. 6, p. 49-61, 2011. http://www.aba-agroecologia.org.br/ojs2/index.php/rbagroecologia/article/view/10626/pdf_1
ZATTA, D.T., BARA, M.T.F., GARROTE, C.F.D., PIMENTA, F.C., TRESVENZOL, L.M.F., FIUZA, T.S. Antibacterial activity of the crude ethanol extract from Jacaranda decurrens leaves. Lat Am J Pharm. vol. 2009, n. 2, p. 297-297, 2009. http://www.latamjpharm.org/trabajos/28/2/LAJOP_28_2_2_5_AAGO5356R7.pdf
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Scientific Electronic Archives

This work is licensed under a Creative Commons Attribution 4.0 International License.
The journal reserves the right to make changes to the original rules, spelling and grammatical order, in order to keep the language of worship default, respecting, however, the style of the authors. The finals will be sent to authors. Articles published are the property of Scientific Electronic Archives magazine, becoming its total or partial reprint, subject to the express authorization of the direction of the journal. The original source of publication should be retained. The originals will not be returned to the authors. Opinions expressed by authors of articles are solely your responsibility.
This journal uses the License Creative Commons Atribuição 4.0 Internacional.