Bioactive Compounds and antioxidant potential of Rhamnidium elaeocarpum (Rhamnaceae)
DOI:
https://doi.org/10.36560/18320252060Palavras-chave:
Rhamnidium elaeocarpum, antioxidant activity, flavonoids, sterols, DPPH, ABTS, lipid peroxidationResumo
This study investigates the antioxidant potential and chemical composition of Rhamnidium elaeocarpum extracts. The purpose was to evaluate the bioactive properties of the plant’s ethanolic extract and identify the key compounds responsible for its effects. The methods involved the preparation of ethanolic extracts followed by assays to measure antioxidant activity, including DPPH radical scavenging, ABTS assay, and lipid peroxidation inhibition. The extract was also analyzed for its phytochemical composition through chromatography techniques. The results showed that the ethanolic extract exhibited significant antioxidant activity, with high radical scavenging capacity and strong inhibition of lipid peroxidation. Major bioactive compounds, including flavonoids and sterols, were identified, which are likely responsible for the observed effects.
Referências
Richardson, J.E.; Chatrou, L.W.; Mols, J.B.; Erkens, R.H.; Pirie, M.D. Historical biogeography of two cosmopolitan families of flowering plants: Annonaceae and Rhamnaceae. Philos. Trans. R. Soc. Lond. B Biol. Sci., v. 359, p. 1495-1508, 2004. DOI: https://doi.org/10.1098/rstb.2004.1537
Alarcón, J.; Cespedes, C.L. Chemical constituents and biological activities of South American Rhamnaceae. Phytochem. Rev., v. 14, p. 389-401, 2015. DOI: https://doi.org/10.1007/s11101-015-9404-6
Lima, R.B.; Giulietti, A.M. Synonymies and typification of the Rhamnaceae of Brazil. Acta Bot. Bras., v. 28, p. 376-381, 2014. DOI: https://doi.org/10.1590/0102-33062014abb3334
Pott, P.; Pott, J.V. Plantas do Pantanal. Corumbá: Embrapa, 1994. p. 244-245.
Lorenzi, H. Árvores brasileiras: manual de identificação e cultivo de plantas arbóreas do Brasil. Nova Odessa: Instituto Plantarum, 1998. p. 89-91.
Oliveira, T.B.; Soares, R.L.; Tresvesol, L.M.F.; Branquinho, D.S.P.; Bara, M.T.F.; Fiuza, T.S.; Rezende, M.H.; Paula, J.R. Caracterização das folhas e cascas de Rhamnidium elaeocarpum Reissek. Latin Am. J. Pharm., v. 29, p. 534-541, 2010.
Kauffmann, A.C.; Oliveira, R.G.S.P.; Dourado, T.A.; Soares, I.N.; Sousa, P.T.; Ribeiro, T.A.N.; Jacinto, M.J.; Souza, G.L.; Judice, W.A.S.; Emiliano, M.F.C.; Vianna, L.S.; Carvalho, M.G.; Silva, V.C.P. Eleocarpanthraquinone, a novel anthraquinone from Rhamnidium elaeocarpum (Rhamnaceae). Tetrahedron Lett., v. 61, p. 152489, 2020. DOI: https://doi.org/10.1016/j.tetlet.2020.152489
Ohkawa, H.; Ohishi, N.; Yagi, K. Assay of lipid peroxidation in animals and tissues by thiobarbituric acid reaction. Anal. Biochem., v. 95, p. 351-358, 1979. DOI: https://doi.org/10.1016/0003-2697(79)90738-3
Parthasarathy, S.; Azizi, J.B.; Ramanathan, S.; Ismail, S.; Sasidharan, S.; Said, M.I.M.; Mansor, S.M. Evaluation of antioxidant and antibacterial activities of aqueous, methanolic and alkaloid extracts from Mitragyna speciosa (Rubiaceae family) leaves. Molecules, v. 14, p. 3964-3974, 2009. DOI: https://doi.org/10.3390/molecules14103964
Aderogba, M.A.; Kgatle, D.T.; Macgaw, L.J.; Eloff, J.N. Antifungal and antibacterial activities of plant extracts. S. Afr. J. Bot., v. 79, p. 125-131, 2012. DOI: https://doi.org/10.1016/j.sajb.2011.10.004
Kojima, H.; Sato, N.; Hatano, A.; Ogura, H. Flavonoid glycosides from the leaves of Zelkova serrata. Phytochem., v. 29, p. 2351-2355, 1990. DOI: https://doi.org/10.1016/0031-9422(90)83073-A
Silva, J.P.R.; Policarpo, I.S.; Chaves, T.P.; Coutinho, H.D.M.; Alves, H.S. A glycosylated β-sitosterol, isolated from Tacinga inamoena (Cactaceae), enhances the antibacterial activity of conventional antibiotics. S. Afr. J. Bot., v. 133, p. 193-200, 2020. DOI: https://doi.org/10.1016/j.sajb.2020.07.017
Sharma, O.P.; Bhat, T.K. DPPH antioxidant assay: A review. Food Chem., v. 133, p. 1202-1205, 2009. DOI: https://doi.org/10.1016/j.foodchem.2008.08.008
Silva, J.R.; Souza, A.O.; Anjos, I.C.; Pádua, G.M.S.; Vieira, L.C.C.; Gai, B.M. Evaluation of chalcones derivatives in lipid peroxidation reduction induced by Fe²⁺/EDTA in vitro. Res. Soc. Dev., v. 12, p. e16012139541, 2023. DOI: https://doi.org/10.33448/rsd-v12i1.39541
Huang, D.; Ou, B.; Prior, R.L. The chemistry behind antioxidant capacity assays. J. Agric. Food Chem., v. 53, p. 1841-1856, 2005. DOI: https://doi.org/10.1021/jf030723c
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