Effects of caffeine on individuals with anxiety disorders: an integrative review

Autores

DOI:

https://doi.org/10.36560/19320262193

Palavras-chave:

Caffeine; Symptoms; Anxiety disorders; Panic; Depression

Resumo

Caffeine is one of the most widely consumed psychoactive substances worldwide, present in beverages such as coffee, tea, soft drinks, and energy drinks. Its main effect is the stimulation of the central nervous system, promoting increased alertness and reduced fatigue. However, its impacts on mental health, especially in individuals with anxiety disorders (who are predisposed), still raise questions. This study aimed to analyze, through an integrative literature review, the effects of caffeine consumption in individuals with anxiety disorders, comparing them to the effects observed in people without this condition, as well as results with differences in dose, sociocultural and genetic factors. The research was conducted using secondary sources available in the PubMed, SciELO, and Google Scholar databases, considering publications between 2015 and 2025, mainly research and studies. The results pointed to a possible relationship between high caffeine consumption and the worsening of anxiety symptoms, such as irritability, insomnia, tachycardia, and restlessness, suggesting the importance of individualized clinical guidance regarding the use of the substance. The study aims to contribute to the conscious use of caffeine and expand knowledge about its effects in more sensitive populations.

Referências

Paz-Graniel I, Kose J, Babio N, Hercberg S, Galan P, Touvier M, Salas-Salvadó J, Andreeva VA. Caffeine intake and its sex-specific association with general anxiety: a cross-sectional analysis among general population adults. Nutrients. 2022; 14(6), 1242.

Richards G, Smith A. Caffeine consumption and self-assessed stress, anxiety, and depression in secondary school children. Journal of Psychopharmacology. 2015; 29(12), 1236-1247.

Santos VA, Hoirisch-Clapauch S, Nardi AE, Freire RC. Panic disorder and chronic caffeine use: a case-control study. Clinical Practice & Epidemiology in Mental Health. 2019. 15, 120.

Pané-Farré CA, Alius MG, Modeß C, Methling K, Blumenthal T, Hamm AO. Anxiety sensitivity and expectation of arousal differentially affect the respiratory response to caffeine. Psychopharmacology (Berlin). 2015. 232(11), 1931-1939.

Kosecka O, Charzyńska E, Czerwiński SK, Rudnik A, Atroszko PA. Caffeine intake mediates the relationship between problematic overstudying and psychological distress. Nutrients. 2025. 17(17), 2845.

Hoppe JM, Björkstrand J, Vegelius J, Klevebrant L, Gingnell, M, Frick A. Acute effects of 150 mg caffeine on subjective, physiological, and behavioral components of anxiety in panic disorder and healthy controls: a randomized placebo-controlled crossover trial. Journal of Psychopharmacology. 2025. 39(8), 836-846.

Makki NM, Alharbi ST, Alharbi AM, Alsharif AS, Aljabri AM. Caffeine consumption and depression, anxiety, and stress levels among university students in Medina: a cross-sectional study. Cureus. 2023. 15(10), e48018, 2023.

Staack A, Distelberg B, Moldovan C, Belay RE, Sabaté J. The Impact of caffeine intake on mental health symptoms in postmenopausal females with overactive bladder symptoms: a randomized, double-blind, placebo-controlled trial. Journal of Women’s Health (Larchmont). 2022. 31(6), 819-825.

Masdrakis VG, Markianos M, Oulis P. Lack of specific association between panicogenic properties of caffeine and HPA-axis activation: a placebo-controlled study of caffeine challenge in patients with panic disorder. Psychiatry Research. 2015. 229(2), 75-81.

Cho JA, Kim S, Shin H, Kim H, Park EC. The association between high-caffeine drink consumption and anxiety in Korean adolescents. Nutrients. 2024. 16(6), 794, 2024.

Publicado

2026-04-13

Como Citar

Pereira, R. L. S., Pereira Lima, C., Garcia Novais, M. H., de Macêdo, D. G., Ribeiro, D. A., de Sousa Júnior, D. L., … Barbosa, M. de O. (2026). Effects of caffeine on individuals with anxiety disorders: an integrative review. Scientific Electronic Archives, 19(3). https://doi.org/10.36560/19320262193

Edição

Seção

Ciências da Saúde
Received 2026-02-21
Accepted 2026-03-06
Published 2026-04-13

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